The Faculty was first established as the Division of Basic Sciences in 1972. Its objective was to offer basic science courses required by other faculties in the University. In 1975, the status of the division was upgraded to a faculty, and named the Faculty of Science and Environmental Studies.
Since then the faculty has gone through several restructuring processes, including the setting up of the Department of Environmental Sciences and the Department of Computer Sciences which later were upgraded to form two new faculties, and the transfer of the Department of Biochemistry and Microbiology to the newly formed Faculty of Biotechnology and Biomolecular Sciences. Ever since the restructuring, the faculty has been renamed as the Faculty of Science in 2004.